![]() ![]() Positive pressure ventilation and positive-negative pressure ventilation are adopted alternately. ![]() In this paper a new concept of removing this dead space of ventilation is presented. This kind of ventilation scheme always generates a prism-shaped dead space of ventilation close to the ground in between the two neighboring ventilation troughs, causing the grain in this area go moujdy. Respiratory mechanics were of no help in optimising PEEP with regard to gas exchange.Granary with ventilation troughs, as widely used in China, is a kind of granaries with rectangular flat base ventilation troughs built on the ground, and positive pressure ventilation is generally adopted. Individual measurements show a diverse response to PEEP. VD fractions were independent of respiratory resistance and compliance.Īlveolar VD is large and does not vary systematically with PEEP in patients with various degrees of ALI. However, in individual patients a decrease and increase of alveolar VD paralleled a positive or negative response to PEEP with respect to oxygenation (shunt), respectively. Alveolar VD was 11-38% of VT and did not vary systematically with PEEP. ![]() Physiological VD was 41-64% of VT at zero PEEP and increased slightly with PEEP due to a rise in airway VD. Lung mechanics and VD were measured at each PEEP level. Stepwise increases in PEEP from zero to 15 cm H2O. Prospective, non-randomised comparative trial. Medical and surgical intensive care unit (ICU) in a university hospital. We investigated how physiological, airway and alveolar VD varied with PEEP and analysed possible links to respiratory mechanics. A low VT and a positive end-expiratory pressure (PEEP) can prevent VILI, but the more VT is reduced, the more dead space (VD) compromises gas exchange. A large tidal volume (VT) and lung collapse and re-expansion may cause ventilator-induced lung injury (VILI) in acute lung injury (ALI). ![]()
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